How Will Unhealthy Americans React to COVID-19 Vaccines?

How Will Unhealthy Americans React to COVID-19 Vaccines?

If you look at the human clinical trials that have been conducted this year by drug companies developing experimental vaccines for COVID-19, the participants in those trials have all been “healthy adults.” Take, for example, Moderna’s Phase 1 clinical trial for its mRNA-1273 vaccine, which included 45 healthy adults 18 to 55 years old. The same is true for the Phase 1/2 clinical trial for the BNT162b1 vaccine being developed jointly by Pfizer and BioNTech. That trial also involved 45 healthy adults between the ages of 18 and 55 years.1 2 3 4 5 6

The Phase 1 clinical trial for CanSino Biologics’ Ad5-nCoV vaccine included 108 healthy adults 45 to 60 years of age. The Phase 1/2 trial for Novavax’s NVX‑CoV2373 was limited to 131 healthy adults 18 to 59 years old. The Phase 1/2 trial for AstraZeneca/University of Oxford’s AZD1222 (formerly ChAdOx1 nCoV-19) vaccine involved 1,077 healthy adults 18 to 55 years of age.7 8 9 10 11 12

There were two age groups in Johnson & Johnson’s Phase 1/2a clinical trial for its Ad26.COV2.S vaccine. The first group consisted of 402 healthy adults 18 to 55 years old. The second group included 394 healthy elderly adults 65 years of age and older.13

All six of these experimental COVID-19 vaccine programs have at least three things in common. First, they have all moved into the Phase 3 clinical trial stage in which tens of thousands of healthy adults are being recruited to continue testing the safety and efficacy of the vaccines. Second, many of the people who participated in the trials experienced adverse events after getting the vaccines. Third, all of the participants were healthy adults.

Experimental COVID-19 Vaccines Have Produced Many Adverse Events

One reason that these COVID-19 vaccine development programs have proceeded to Phase 3 clinical trials is that the drug companies behind them determined that the earlier trials showed the vaccines stimulated sufficiently strong antibody responses by the immune system to merit further research and testing. The companies also judged the vaccines to be “generally considered” safe, 14 15 16 17 18 19 20 21 22 23 24 25 even though the vaccines provoked adverse events in dozens of trial subjects—including some serious or severe adverse events, as in the case of the Moderna mRNA-1273, Pfizer/BioNTech BNT162b1, CanSino Biologics Ad5-nCoV, Novavax NVX‑CoV2373 and Johnson & Johnson Ad26.COV2.S vaccines.1 2 4 7 9 25

No serious or severe adverse events were reported in the Phase 1/2 trial for the AstraZeneca/University of Oxford AZD1222 vaccine before AstraZeneca announced on Sept. 8, 2020 AstraZeneca that it was pausing its Phase 3 trials on the vaccine in United States and the United Kingdom to investigate a case of transverse myelitis (a neurological condition caused by inflammation of the spinal cord) suffered by one of the volunteer trial participants.  26 27

Phase 3 Clinical Trial for AZD1222 Still Paused Pending FDA Safety Review

The Phase 3 trial in the U.K. was resumed on Sept. 12 following a review by officials at the U.K.’s Medicines Health Regulatory Authority (MHRA), who reportedly concluded that it was safe to do so. The clinical trial in the U.S. remains on hold while the U.S. Food and Drug Administration (FDA) is investigating the “unexplained illness.” Recent news reports indicate that the FDA may, in fact, be expanding its investigation. FDA commissioner Stephen Hahn said:

We’re here to protect the American public and we’re going to do very significant work with the company to figure out if there’s a significant safety issue or not.28 29

Consistently, reports about the adverse events experienced by clinical trial participants receiving experimental COVID-19 vaccines have tended to downplay the events, with company spokespersons noting that vaccine reactions have been “mild or moderate” and short-lived. While they didn’t hide the fact that there were numerous serious or severe adverse events to the vaccines, neither did they highlight these reactions. Nor did they raise many concerns about the unknown long-term effects of all vaccine adverse events, regardless of their severity.3 12 25 30 31 32

Most People in the U.S. are Not Healthy

Perhaps most concerning is the apparent neglect to acknowledge the elephant in the room, which leads to the obvious question being asked by many Americans concerned about the safety of experimental COVID-19 vaccines being rushed to market: “If these vaccines are only being primarily tested on healthy adult volunteers under age 65 and a good number of them are suffering vaccine adverse events, then how will the elderly over age 65 and unhealthy adults and children react to the vaccines?”

This is not an insignificant question, given that most Americans are not healthy. Six out of 10 adults in the U.S. suffer from a chronic disease. Four out of 10 adults in the U.S. suffer from two or more chronic diseases. An estimated 10-20 million (13.5 to 27 percent) American children and adolescents suffer from a chronic illness or disability. An estimated 42.4 percent of adults in the U.S. are obese—9.2 percent qualify as severely obese. An estimated 13.7 million (18.5 percent) American children and adolescents qualify as obese. More than 131 million Americans, or 66 percent of all adults in the U.S., take prescription drugs.33 34 35 36 37

A study published in the journal Mayo Clinic Proceedings in 2016 found that less than three percent of Americans live a health lifestyle. Another study published in the journal Metabolic Syndrome and Related Disorders in 2018 found that only 12 percent of adults in the U.S. are metabolically healthy. These kind of studies abound.38 39

A sick and medicated America is the new norm. Tens of millions of children and adults in the U.S. are not healthy. How many and what kind of adverse events should they expect from experimental COVID-19 vaccines that are only being tested on healthy adults over a short period of time?


1 Cáceres M. Healthy Clinical Trial Subjects Suffer Grade 3 Side Effects to Moderna’s mRNA COVID-19 Vaccine. The Vaccine Reaction May 24, 2020.
2 Cáceres M. Volunteer Describes His Serious Reaction in Moderna’s mRNA COVID-19 Vaccine Trial. The Vaccine Reaction May 30, 2020.
3 Jackson LA, et al. An mRNA Vaccine against SARS-CoV-2 — Preliminary Report. NEJM July 14, 2020.
4 Cáceres M. Pfizer/BioNTech’s COVID-19 Vaccine Causes Adverse Reactions in Over Half of Clinical Trial Volunteers. The Vaccine Reaction July 18, 2020.
5 Mulligan MJ, et al. Phase 1/2 Study to Describe the Safety and Immunogenicity of a COVID-19 RNA Vaccine Candidate (BNT162b1) in Adults 18 to 55 Years of Age: Interim ReportmedRxXiv July 1, 2020.
6 U.S. National Library of Medicine. A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults. May 12, 2020.
7 Cáceres M. 81 Percent of Clinical Trial Volunteers Suffer Reactions to CanSino Biologics’ COVID-19 Vaccine That Uses HEK293 Human Fetal Cell Lines. The Vaccine Reaction July 6, 2020.
8 Liu A. China’s CanSino Bio advances COVID-19 vaccine into phase 2 on preliminary safety data. Fierce Pharma Apr. 10, 2020.
9 Cáceres M. Novavax’s Adjuvanted COVID-19 Vaccine Caused Severe Adverse Reactions in Clinical Trials. The Vaccine Reaction Sept. 14, 2020.
10 Keech C, et al. Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle VaccineNEJM Sept. 2, 2020.
11 Cáceres M. A Grade 3 Vaccine-Related Adverse Event is Serious. The Vaccine Reaction July 26, 2020.
12 Folegatti PM, et al. Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial. The Lancet July 20, 2020.
13 Sadoff J, et al. Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate: interim results of a phase 1/2a, double-blind, randomized, placebo-controlled trial. medRxiv Sept. 23, 2020.
14 Press release. Experimental COVID-19 vaccine safe, generates immune response. U.S. National Institutes of Health July 14, 2020.
15 Weintraub K, Heath D. Moderna’s COVID-19 vaccine candidate appears to be safe and provide some immunity, new data from early trial shows. USA Today July 15, 2020.
16 Gumbrecht J, Thomas N, Vigue D, Howard J. Oxford’s Covid-19 vaccine appears safe and induces immune response, early results suggest, but more research is needed. CNN July 21, 2020.
17 Mundell EJ. Pfizer’s COVID Vaccine Shows ‘Robust’ Results in Early Trial. U.S. News & World Report Aug. 12, 2020.
18 Phelamei S. Chinese COVID-19 vaccine appears safe in early human trial: CanSino Bio’s Ad5-nCoV triggers immune response. May 23, 2020.
19 PRNewswire. COVID-19 Vaccines Test Safe & Effective by China & UK teams: the Lancet. Science and Technology Daily July 23, 2020.
20 HospiMedica International staff writers. New Novavax COVID-19 Vaccine Phase 1 Data Reaffirms Safety Profile and Ability to Elicit Immune Response. Sept. 7, 2020.
21 Phelamei S. Novavax coronavirus vaccine appears safe in early trials; J&J COVID jab prevents severe illness in hamsters. Sept. 4, 2020.
22 Elam Y. Coronavirus: Oxford/AstraZeneca Phase 1/2 trial shows safe, immunogenic vaccine, S&P 500 positive. FXStreet July 20, 2020.
23 Gumbrecht J, Thomas N, Vigue D, Howard J. Oxford vaccine is safe and induces immune response, early results suggest. CNN July 21, 2020.
24 Kallingal M, Kane A, Bonifield J, Mascarenhas L. Johnson and Johnson vaccine produced strong immune response, early results say. CNN Sept. 24, 2020.
25 Sadoff J, et al. Safety and immunogenicity of the Ad26.COV2.S COVID-19 vaccine candidate: interim results of a phase 1/2a, double-blind, randomized, placebo-controlled trial. medRxiv Sept. 23, 2020.
26 Cáceres B. AstraZeneca Halts, Resumes COVID-19 Vaccine Trial After Serious Neurological Event. The Vaccine Reaction Sept. 14, 2020.
27 Transverse myelitis. Mayo Clinic.
28 Press release. COVID-19 vaccine AZD1222 clinical trials resumed in the UK. AstraZeneca Sept. 12, 2020.
29 Genovese D.  FDA widens probe into AstraZeneca’s US coronavirus vaccine trial: report. Fox Business Oct. 1, 2020.
30 Garde D. Novavax’s Covid-19 vaccine shows promising immune response, early data show. STAT Aug. 4, 2020.
31 Feng-Cai Z, et al. Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial. The Lancet June 13, 2020; 395: 1845-1854.
32 Press release. Pfizer and BioNTech share positive early data on lead mRNA vaccine candidate BNT162B2 against COVID-19. Pfizer Aug. 20, 2020.
33 Chronic Diseases in America. U.S. Centers for Disease Control and Prevention.
34 Chronic. HealthChildren.og.
35 Adult Obesity Facts. CDC.
36 Childhood Obesity Facts. CDC.
37 Healthy Policy Institute. Prescription Drugs. Georgetown University McCourt School of Public Policy.
38 Beck J. Less Than 3 Percent of Americans Live a ‘Healthy Lifestyle’. The Atlantic Mar. 23, 2016.
39 University of North Carolina at Chapel Hill. Only 12 percent of American adults are metabolically healthy, study finds. Medical Xpress Nov. 28, 2018.

Note: This commentary provides referenced information and perspective on a topic related to vaccine science, policy, law or ethics being discussed in public forums and by U.S. lawmakers.  The websites of the U.S. Department of Health and Human Services (DHHS) provide information and perspective of federal agencies responsible for vaccine research, development, regulation and policymaking.


11 Responses to "How Will Unhealthy Americans React to COVID-19 Vaccines?"

  1. Ellen   October 5, 2020 at 4:51 pm

    These are questions that have existed for a great many years…..with no answers forthcoming from BigPharma…..and none being asked publicly. The fact that the vaccine makers have little to no accountability SHOULD make people very wary of these concoctions. However, few are aware of that huge elephant in the room.

    The medical tyranny being forced on a supposedly free people in the U.S. is appalling. That so many obsessively wash their hands, use the alcohol preparations on their hands, socially isolate themselves and wear their face diapers willingly, speaks volumes about the level of education of a great many in this country. The whole agenda is to kill an organism; never mind that it is the human physiology that does the work and must be nourished and supported. The medical mafia are in their glory with so many worshiping the dogma of the long debunked germ theory. I cannot even look at these faceless, 2-legged beings.

    A doctor teaches……ours learned at the altar of BigPharma and consult their “this for that” cookbook when someone has some difficulty. They teach nothing except to shove a pill down the gullet or get jabbed with very dangerous mixtures. When a people take no responsibility for their own health by FIRST supporting their bodies, we have a nation that is steadily declining.

  2. Colorado   October 5, 2020 at 4:55 pm

    And here I am, caring if my soap and shampoos were humanely developed and not tested on bunnies and monkeys… Buying organic foods, trying to save the bees and myself.

    So much for ethics in product development. How stupid do you have to be to presume injecting toxins into your system will result in better health. A barbaric practice indeed. Ghandi.

    Yet I don’t mind if other people take it. Darwin awards for everyone who lines up. Hopefully they will die off because overpopulation is inevitable on this planet. Think of the vaccination propaganda lobby as an intelligence test. You either pass it and refuse, or you don’t, and you take the vaccines.

  3. Dorothy Kearney   October 5, 2020 at 5:33 pm

    Well, it is a way to eliminate those considered to be a burden to society.

  4. Tom   October 5, 2020 at 6:48 pm

    This is very chilling. If I am healthy and not on any drugs (age 70) why do I need a vaccine? I haven’t had a flu shot in 40 years and seldom get sick. I believe vaccines and drugs hamper the ability of the immune system to fully function. This is by design since any pharma company and the fraudulent medical system cannot survive or make oodles of profits if people are healthy. Keep ’em sick with vaccines and drugs and there will be a steady line of patients requiring more drugs and whatnot that do even more damage to the body. Big Pharma has created an endless stream of false belief that vaccines and drugs work and it’s all based on FEAR. Not a smidgen of anything about living healthier, vitamins and minerals which is what the body needs to function properly and more of them as you age…not more drugs.

  5. Christina Morton   October 6, 2020 at 7:01 am

    You’d think anyone with ‘1/2 a brain ‘ would figure if no accountability, no reason to do the right thing… let alone give a damn….What will it take for people to get their head around the fact that no government or Big Pharma cares about you or your health …It’s always been about the money and control….. here we are 7 months later…keeping the fear mongering and lies going….still not questioning
    everything you’re told on mainstream TV … the proof is out there for all to see… your own research …(Independent doctors and scientists)

  6. Brian James   October 7, 2020 at 3:43 pm

    Oct 1, 2020 Exclusive Sneak Peek of The Truth About Vaccines 2020 Docu-Series

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  7. Brian James   October 7, 2020 at 6:36 pm

    OCTOBER 6, 2020 Register For The Truth About Vaccines: October 13-23!

    Note: This article is for informational purposes only and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider.

  8. Brian James   October 7, 2020 at 6:39 pm

    This link should work I do not what happened in my other post. My apologies!

  9. Pa   October 9, 2020 at 1:17 pm

    Pretty much, Big Pharm, Gates, Fauci and all the players are going to profit from all of this lying and deception, they already are. Given the number of people who may be forced to take the vaccine if mandated by their local governments (hopefully the president will NOT mandate it), there will be a serious thinning of the population. Gates will get his wish to depopulate as well as make a fortune, Fauci will remain with the underlords of darkness (WHO, CDC and others) to continue to create a market for more vaccines (more patented virus’s). Gates already stated if people don’t take this serious this time, they will the next with a smirk on his pathetic face. So, if these villains are not brought to justice for intentional Genocide, we are all at risk of being poisoned for profit. Lose the mask already!!

  10. ikara   October 9, 2020 at 5:31 pm

    On the topic of mandatory vaccination, are we considering this action on the basis of public health? What about those for whom vaccination will harm their health (e.g., those with the MTHRF gene mutation which makes them more susceptible to mild to serious vaccine injuries; see here for one such study concluding this: What about those who do not wish to be injected by the ingredients in vaccines that go against their beliefs and/or who do not wish to be injected by ingredients that have not been individually tested in a double-blind, saline placebo-controlled study? See here for a list of ingredients in vaccines currently on the market (which would give a good indication of what will be in the CV-19 vaccine: ).

    Such questionable ingredients that inquiring minds may not wish to inject into their own bodies and those of their children include aborted fetal cells (MRC-5 is from a male, and WI-38 is from a female)–which goes against our respect for the sanctity of all life (and all life starts at conception). Other toxic ingredients include formaldehyde, aluminum (e.g., aluminum hydroxide, aluminum phosphate, aluminum salts, amorphous aluminum, and hydroxyphosphate sulfate), monosodium glutamate (MSG), polysorbate 80 and 20(which opens the protective blood-brain barrier and allows toxins to filter into the brain), animal cells (e.g., VERO cells, fetal bovine serum, monkey kidney cells, Madin Darby Canine Kidney, egg protein, African Green Monkey kidney, hydrolyzed porcine, etc.), magnesium stearate, EDTA, and trace amounts of thimerosal (mercury).

    We must, also, consider that no vaccine is 100% safe and effective. In fact, the Supreme Court stated some time ago that all such injections are “unavoidably unsafe” (see here:, and the volume of adverse reactions reported to VAERS (Vaccine Adverse Events Reporting System) shows this clearly to be the case (see here:, even if “… fewer than 1% of vaccine adverse events are reported” (which would make the number of actual adverse events potentially much, much higher (see this article about its safety:

    According to many independent researchers and doctors who have critically examined the studies claiming that they are ‘safe and effective,’ these injections are neither safe nor effective and have never been proven to be the case through well-designed and trustworthy studies (see this peer-reviewed article on why most clinical research is not useful:

    So considering that injections are considered “unavoidably unsafe” and that the conclusions that they are ‘safe and effective’ are drawn from poorly-designed, short-term safety studies with conflicts-of-interest and with study participants who do not reflect the vast population of people who are intended recipients of it, how is it that the government–who is tasked with preserving out God-given rights–can consider mandating a vaccine to be injected into the bodies of all without the option of informed consent in the matter? Does the government own the body of each man, woman, or child? Who will be responsible for those who are injected with a mandatory vaccine (whether or not they are forced against his or her will) and experience a negative reaction to it?

    And in case anyone is interested in more information on the CV-19 vaccine, here is Dr. Sherri Tenpenny talking about it:

    And this person understands this topic well and reports on alarming information about how the CV vaccine works (hint: by changing a person’s genetic code):

    Lastly, here’s clip to a recent, rare (perhaps never-done-before) debate on mandatory vaccination between lawyers Kennedy Jr. (who is for vaccine choice and founder of and Dershowitz (who argues that government-mandated vaccines are acceptable if there is a ‘need’ for them for the ‘greater good’):–lL8rEgsNzvWYm_D70S5uA6xeN-gD2ksKmw

    I hope this helps to shed light on this topic and the necessity for vaccination to be based on voluntary, willing, informed consent–and not on coercion and the threat of the loss of freedoms for those who do not wish to risk their and their children’s long-term health by accepting an injection that touts to protect one from a disease that appears to have a very low infection fatality rate, akin to the seasonal flu. Eat well and keep healthy by avoiding environmental toxins and exposures, keeping active, and eating organic and your body will support you in your goal towards good health.

  11. jennyM   October 13, 2020 at 8:51 pm

    A friend of the family was having issues with IBS and went to get a flu shot. I tried to talk them out of it but they sadly still buy into the vaccine cult After getting the shot, she got even worse IBS symptoms and her normal IBS meds are not helping. She hasn’t been well since getting the shot. And, of course they’ll never suspect the vaccine as causing anything bad.


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