Monday, April 22, 2024


“You may choose to look the other way, but you can never say again that you did not know.”

— William Wilberforce


81 Percent of Clinical Trial Volunteers Suffer Reactions to CanSino Biologics’ COVID-19 Vaccine That Uses HEK293 Human Fetal Cell Lines

ill woman with hand on forehead

An experimental vaccine for COVID-19 is being developed by CanSino Biologics, Inc. of Tianjin, China, in partnership with China’s Academy of Military Medical Sciences’ Institute of Biotechnology. A Phase 1 human clinical trial of the COVID-19 vaccine (adenovirus type-5 Ad5-nCoV) has been completed in China involving 108 healthy adults, ranging in age from 45–60 years old.1 2 3 4

In that trial, 87 (81 percent) of the 108 participants suffered at least one adverse reaction within seven days after vaccination. Of these, 30 of the human subjects were in the low dose group, 30 were in the middle dose group, and 27 were in the high dose group. Overall, 10 of the participants experienced Grade 3 adverse reactions. Of the 36 participants in the high dose group, six of them had Grade 3 adverse reactions.1 2

Pain, Fever, Fatigue, Headache Most Common Reactions to CanSino’s Ad5-nCoV Vaccine for COVID-19

According to researchers conducting the study on the Phase 1 clinical trial for the Ad5-nCoV vaccine:

The most common injection site adverse reaction was pain, which was reported in 58 (54%) vaccine recipients. Pain was reported in 17 (47%) participants in the low dose group, 20 (56%) participants in the middle dose group, and 21 (58%) participants in the high dose group. The most commonly reported systematic adverse reactions overall were fever (50 [46%]), fatigue (47 [44%]), headache (42 [39%]), and muscle pain (18 [17%]). Fever was reported in 15 (42%) participants in the low dose group, 15 (42%) participants in the middle dose group, and 20 (56%) participants in the high dose group. Headache was reported in 14 (39%) participants in the low dose group, 11 (31%) participants in the middle dose group, and 17 (47%) participants in the high dose group. Muscle pain was reported in seven (19%) participants in the low dose group, three (8%) participants in the middle dose group, and eight (22%) participants in the high dose group.2

Nine of the participants, including two in the low dose group, two in the middle dose group and five in the high dose group developed Grade 3 fevers of over 101.3°F. One of the participants in the high dose group reported “severe fever along with severe symptoms of fatigue, dyspnoea, and muscle pain.” Another participant in the high dose group experienced “severe fatigue and joint pain.” The reactions happened within 24 hours after vaccination.1 2

Moderna’s Experimental mRNA-1273 COVID-19 Trials Also Noted Grade 3 Reactions

Like in the Phase 1 Ad5-nCov vaccine trial conducted by CanSino, some participants in the Phase 1 trial of the mRNA-1273 COVID-19 vaccine conducted by Moderna, Inc. earlier this year also experienced Grade 3 reactions. Of the 45 volunteers who participated in the Moderna clinical trial during March-May 2020, nine percent of them experienced severe adverse reactions to the mRNA-1273 vaccine, including 29-year-old Ian Haydon of Seattle, Washington.1 2

Haydon suffered Grade 3 reactions 12 hours after getting the second of two 250 µg doses of the mRNA-1273 vaccine. He developed a fever of over 103 degrees and eventually fainted.1 2

Grade 3 reactions are described by the U.S. Department of Health and Human Services (HHS) as, “severe or medically significant but not immediately life-threatening; hospitalization or prolongation of hospitalization indicated; disabling; limiting self care” such as “bathing, dressing and undressing, feeding self, using the toilet, taking medications.” The only thing worse than Grade 3 events are those classified as Grade 4, which is “life-threatening” and “Grade 5, which is “death.”5 6 7

CanSino Now Running Phase 2 Human Clinical Trials on Ad5-nCoV Vaccine for COVID-19

CanSino Biologics has reportedly begun a Phase 2 human clinical trial of Ad5-nCoV vaccine using the HEK293 cell line that involves testing on 500 healthy volunteers. On May 12, the National Research Council of Canada (NRC) announced a collaborative agreement with the Chinese company to “advance bioprocessing and clinical development in Canada” of the Ad5-nCoV vaccine.4 8 9 10

In a press release, the NRC stated, “This collaboration will allow the NRC to advance a scale-up production process for the vaccine candidate, using its proprietary HEK293 cell line.”9 10

To facilitate this work, the Canadian government announced it would provide $44 million to upgrade the NRC facilities in Montreal to “enable compliance with Good Manufacturing Practice (GMP) standards” and to “ensure readiness for Canadian bioprocessing of potential vaccine candidates as they become available.”9

“It is perfect timing to leverage cutting-edge technology and resources from both sides that are critical to the development of Ad5-nCoV,” said Xuefeng Yu, CEO of CanSino Biologics.10

CanSino Ad5-n-CoV Vaccine Uses HEK-293 Human Fetal Cell Lines for Production

Life Site News reported on June 26, 2020 that CanSino’s Ad5-n-CoV vaccine employs a chimpanzee adenovirus vector that uses the HEK293 cell lines derived from tissue of an aborted fetus.11 The HEK293 human fetal cell line, which was designed, developed and is licensed by Canada’s National Research Council (NRC), is also being used to produce the AZD1222 COVID-19 vaccine developed by the University of Oxford’s Jenner Institute.

The May 12, 2020 joint press release issued by Canada’s NRC and CanSino Biologics, Inc. stated,“The relationship between the NRC and CanSinoBIO was first established in 2013. The NRC’s HEK293 cell line was later licensed to CanSinoBIO and used in the development of an approved vaccine against the Ebola virus.”12

According to News Medical:

The HEK293 cell line was initially produced in 1973 by a team led by Alex van der Eb in Leiden (Netherlands) from normal fetal human embryonic kidney cells. These cells were created following transfection with sheared adenovirus 5 DNA, leading to the incorporation of some of the adenoviral genome into the human chromosome 19 of the fetal cell’s genome. The name 293 comes from the fact that it was Frank Graham’s (one of van de Eb’s postdoc) 293rd experiment. These cells were initially thought to originate from an endothelial, epithelial, or fibroblastic cell from the fetal kidney. However, recent evidence into the cellular characteristics of HEK293 cells has led to the suggestion that they may actually originate from a neuronal fetal kidney cell. Following sequencing studies, it has also been identified that these cells have a very complicated karyotype, with multiple copies of chromosomes. For example, these cells have four copies of chromosome 17. It has also been established that these cells do not have a single Y chromosome—but have three X chromosomes—suggesting that the fetus from which they were obtained was a female.13

The HEK293 cell is described by Creative Biolabs this way:

The Human Embryonic Kidney 293 (HEK293) cell line is a predominant host for both stable expression and transient expression of various research grade proteins and protein therapeutics, and more recently, five therapeutic agents produced in HEK293 cells have been approved by the FDA or the European Medicines Agency (EMA) for therapeutic use. Since being generated over 40 years ago, the HEK293 cell line has been extensively used as a robust and reliable platform to produce plenty of recombinant antibodies, antibody fusion proteins and proteins important to the neuropharmacologist, such as G protein coupled receptors, ligand-gated ion channels, and voltage sensitive ion channels. The HEK293 cell line was originally generated by the transformation of normal human embryonic kidney (HEK) cells following exposure to sheared fragments of human adenovirus type 5 (Ad5) DNA. The E1A adenovirus gene is expressed in these cells and participates in transactivation of some viral promoters, allowing these cells to produce very high levels of protein.14


1 Branswell H. Early study of Covid-19 vaccine developed in China sees mixed results. STAT May 22, 2020.
2 Hou LH, et al. Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial. The Lancet June 13, 2020; 395 (10240): 1845-1854.
3 Liu A. China’s CanSino Bio advances COVID-19 vaccine into phase 2 on preliminary safety data. Fierce Pharma Apr. 10, 2020.
4 U.S. Food and Drug Administration. CanSino Biologics Moves COVID-19 Vaccine Candidate Into Phase 2 TrialFDA News Apr. 14, 2020.
5 Cáceres M. Healthy Clinical Trial Subjects Suffer Grade 3 Side Effects to Moderna’s mRNA COVID-19 Vaccine. The Vaccine Reaction May 24, 2020.
6 Cáceres M. Volunteer Describes His Serious Reaction in Moderna’s mRNA COVID-19 Vaccine TrialThe Vaccine Reaction May 30, 2020.
7 U.S. Department of Health and Human Services. Common Terminology Criteria for Adverse Events (CTCAE). Nov. 27, 2017.
8 Rettner R. Coronavirus vaccine developed in China shows promise after early study in 100 people. Fox News May 27, 2020.
9 Press Release. The National Research Council of Canada and CanSino Biologics Inc. announce collaboration to advance vaccine against COVID-19. National Research Council of Canada May 12, 2020.
10 Dearment A. CanSino Biologics may start clinical development of Covid-19 vaccine in Canada. MedCity News May 13, 2020.
11 Murdoch A. UK university test COVID-19 vaccine derived from aborted fetal cell line in Africa, Brazil. Life Site News June 26, 2020.
12 Bloomberg. NRC of Canada and CanSino Biologics, Inc. announce collaboration to advance vaccine against COVID-19. May 12, 2020.
13 Simmons H. HEK293 Cells: Applications and Advantages. News Medical Jan. 8, 2019.
14 Creative Biolabs. HEK293 Cell Lines. 2020.

20 Responses

  1. They will be sick for life. No one knows if the DNA or self replicating RNA is cancerous or has other issues. How heinous.

  2. Anyone STUPID enough to take any vaccine that has never been tested against an inert placebo…DESERVES to be damaged.

  3. Thanks for the article!

    Jul 12, 2019 The Threat of Fetal DNA In Vaccines

    Dr. Theresa Deisher presents the dangers of residual human fetal DNA fragments are an unstudied risk to vaccine recipients, yet there’s a growing scientific body of knowledge demonstrating the high likelihood of autoimmune response and gene mutations in children with a genetic vulnerability.

  4. Why is our government allowing the drug manufacturing companies to put another human’s DNA into our vaccines? Why is the medical community allowing it?

    1. Follow the money. The medical community makes more money off of Covid diagnoses and deaths than other diagnoses, including underlying health conditions like heart disease, COPD, asthma, and cardiovascular diseases. Healthcare community makes loads of money off of vaccines, which are covered by Medicare and mainstream health insurance coverage.

  5. 81%. Wow that is a very bad number. And no way in h*ll will someone be shoving a needle into my arm with this. No way.

  6. Quick fix vaccines are the prescription to long lasting side affects with no recourse against the manufactures. I will let my immune system by my vaccine, not the Big Pharma poisons where the side effects are hidden from consumers.

  7. Yep. They/volunteers (((were))) healthy- until that fatal decision. Now they’re just screwed.

  8. Clearly, there is no single “Umbrella Corporation,” as in movies; rather, they are legion.
    China might be the most dangerous–not only due to vast manpower, but also no possible world oversight, short of war—-which obviously we’ve feared, for decades.

    In the USA, since the 1986 indemnification of vaccines, more viruses were needed–in order to claim vaccines had some use in fighting them. The HIV=AIDS hoax taught the powers they could become rich-filthies, by pushing the hardy-tested industrial chemicals (incl., severe contaminations), as if helpful drugs.
    All that’s left is forced vaccinations, to increased the demographic (but I guess that will be finite). Those getting paid soonest don’t are about the future.

  9. Citizens in Charge-a single issue voting bock-the issue: “the right to refuse vaccination for myself and my minor children” This will be THE issue.

  10. There will never be an effective vaccine for this Covid 19…It is a coronavirus. These viruses mutatate with time..meaning they will never be the same. This is why some people react differently to it. Some have severe symptoms and some moderate and some none. The common cold is a corona virus. Do we have a cure? no..Is there a vaccine for it? no
    Will a Covid 19 vaccine work … no.
    Think about this people!
    If one is developed I would be very cautious about it’s authenticity and effectiveness to prevent disease.
    How can a rushed vaccine be effective?… Well it can’t. simple. Vaccines need to be tested for years with follow up on side effects, and still some aren’t proven to prevent any virus or disease.

  11. Back in 2011, when Mexico suffered the H1N1 pandemic in the first months of that year, vaccine producers rushed to create a quick fix vaccine. It was ready around September, 8 months after the pandemic broke out. Fortunately H1N1 was controlled in two months thanks to our then President Calderón who took the matter seriously, unlike President López who has done nothing to control CV19. I received the vaccine in November 2011. A week later I was feeling terrible, with unbearable pain in all my lymphatic system. When examined, doctors (four of them) thought I had leuchemiae. I became allergic to many drugs and may not receive a vaccine containing a live virus. I think the problem was these residual fetal tissues.

  12. since there are human & chimp additions, WHY would we want that injected? Csnnibistic?

    They used to make vccines from chicken eggs?

    ARE THERE ANY KNOWN MILITARY RECORDS ON SIDE EFFECTS FROM THE ADENO VACCINES? Why did they even pick that kind? A. Fauci paid Houston’s Greffex $19 million, last fall, for a corona vaccine, from their adeno. HE knew what was coming? But we got nothing, from that money?

  13. So first we get the VIRUS from China, next we are supposed to line up for a SHOT from China which will likely sicken us short-term, no telling about long-term effects. I don’t like the looks of this. From Gary Jennings: (F) “Report for your execution tomorrow.”

  14. Hello wake up
    Bill gates , eugenics , depopulate the world by 15% (in bills words)
    Ipsos mori (the company working with nhs to test vaccines) ipsos mori in latin means they die

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