Synthetic Flu Vaccine Created As a Pill

Synthetic Flu Vaccine Created As a Pill

scientist and tubes
Unlike traditional biologics, which are built around a killed or weakened pathogen, the new technology uses synthetic “pathogen-like proteins that are ‘mirror images’ of those found in real flu viruses.”

Welsh scientists from Cardiff University in the United Kingdom have developed the first synthetic, non-biologic influenza vaccine, suggesting the discovery may herald a dramatic change in the way vaccines are produced and delivered.1

The new vaccine can be given orally in pill form and does not need to be refrigerated, both doing away with needles and also making it potentially safer, easier and less expensive to distribute. The researchers hope the “pill” vaccine could be especially useful in dispensing vaccines in developing countries, where maintaining the cold chain necessary to protect the integrity of a vaccine has always been a challenge.

Apart from the fact that the new type of influenza vaccine can remain stable at room temperatures, there are other important features that set it apart from other vaccines. Unlike traditional biologics, which are built around a killed or weakened “live” virus or bacteria, the new technology uses synthetic “pathogen-like proteins that are ‘mirror images’ of those found in real flu viruses.”2

Lead researcher Professor Andrew Sewell explained:

The carbon molecules that form all proteins on Earth are left-handed molecules, but they also have a non-biologic, right-handed form. Even though these two forms of a molecule look identical at first glance they are actually mirror images of each other, just like our right and left hands, and cannot be superimposed on each other. The left-handed forms of proteins are easily digested and do not last long in nature. The unnatural, right-handed forms of these molecules are vastly more stable.1

Thus far, the experimental pill influenza vaccine has been studied only in a laboratory setting using both mice and human cells. However, the vaccine developers noted that the test vaccine did “provoke an immune response in human cells in a culture dish and was also found to be as effective as standard biological vaccines when tested in mice.”3

Divya Shah, from Wellcome’s Infection and Immunobiology team said: “This is a very exciting first proof of concept study that could provide a potential route to make vaccines that are thermostable and can be administered orally… however much more research is needed to translate the findings into real-world vaccines.”4

Testing in humans is still years away, but Cardiff researchers are optimistic, saying, “Our demonstration that unnatural molecules, like these mirror image molecules, can be successfully used for vaccination opens up possibilities to explore the use of other unnatural, stable molecular ‘drugs’ as vaccines in the future.”1


References:

1 Short J. Scientists Create World’s FirstSynthetic, Non-Biologic Vaccine. Cardiff University Mar. 13, 2018.
2 Thompson A. Flu Vaccine that can be taken as a PILL is Being Developed by British Scientists. Daily Mail Mar. 13, 2018.
3 Hargreaves B. World’s First Synthetic, Non-Biologic Vaccine Developed. Pharmafile Mar. 14, 2018.
4 Pharmacy Network. Flu Vaccine in Pill Form Breakthrough. Independent Community Pharmacist Mar. 13, 2018.

9 Responses to "Synthetic Flu Vaccine Created As a Pill"

  1. RIck   March 28, 2018 at 6:50 am

    Just as long it as safe as me eating and Apple I cool with it.

    Reply
  2. Jo   March 28, 2018 at 7:14 am

    How will the drug co’s be able to continue to lie about the ‘high costs’ of vaccine/virology R&D? How will they continue to get overpaid enough to give the massive kickbacks to government career criminals? How will they get their Giant Government Grants? How will they continue to get outrageous immunity from lawsuits?

    This technology will have to be buried.
    Any truth or accountability to too-fat-to-fail Big Pharma or Gov would be unprofitable.
    The Filthy Rich intend to remain so.
    YOU are Not “Represented.”

    Reply
  3. Colorado   March 28, 2018 at 8:04 am

    And how exactly does the human body take in, process, then dispel these synthetic molecules? In food, synthetics have become an emerging health issue in the past decade and longer. Everything from flavoring to color additives to substrates and even some vitamin supplements can be synthetic and present in food. These are known health issues because of biological processing difficulties, the synthetic molecule is notorious for being more difficult to process. It is intriguing however, the thought of this passing through a safer digestive route, not being sent directly into the blood. How will biofauna react to this particular synthetic molecule? What is it exactly?

    Reply
  4. Joseph S. Carrilho   March 28, 2018 at 9:00 am

    Click “Best ion Video” below and watch the first video displayed entitled:

    “Baylor’s Doc Hotez Bullies Parents of Vaccine Injured Children | Barbara Loe Fisher”

    Barbara hit this one out of the park. I love this brave patriot!!!

    Reply
  5. Carly Pressman   March 28, 2018 at 9:02 am

    I sure hope this doesn’t contain the toxic chemicals that traditional flu shots contain. That way, we won’t have to worry about getting sick

    Reply
  6. Bill   March 28, 2018 at 11:40 am

    I can’t help but think of an old quote: “The left hand doesn’t know what the right hand is doing”…. How appropriate! Are these UN-natural “right-handed” molecules persistent? Do they bio-accumulate in the body? If indeed these pills are “years away” from even human testing, then how can the researchers so confidently say they could be used as vaccines? “Years away from human testing” ALSO means MANY years away from human use and marketing. This story might sound good to Wall St. investors, but we human guinea pigs need to be VERY cautious.
    (c)2018, Tom Clancy, Jr., *NON-fiction

    Reply
  7. T   March 28, 2018 at 12:08 pm

    Interesting! Wonder what the other ingredients are…

    Reply
  8. happy wheels game   April 5, 2018 at 2:49 am

    Everything from flavoring to color additives to substrates and even some vitamin supplements can be synthetic and present in food. !

    Reply
  9. gmail.com   June 25, 2018 at 8:52 pm

    Everything from flavoring to color additives to substrates and even some vitamin supplements can be synthetic and present in food.

    Reply

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