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COVID-19 Shots Linked to Higher Incidence of Alzheimer’s Disease

brain injury

Several studies during the past two years have shown a link between COVID-19 vaccination and the development of neurological complications involving different types of brain dysfunction, including Alzheimer’s disease. The most recent of these studies was published earlier this year in the British medical journal QJM: An International Journal of Medicine. Researchers investigated the association between COVID vaccination and the onset of Alzheimer’s disease (AD) and its prodromal state, mild cognitive impairment (MCI).1 2 3 4 5

The retrospective cohort study in QJM was conducted by researchers at Korea University College of Medicine in Seoul, South Korea. It used data from the Korean National Health Insurance Service (NHIS) involving 558,087 people, analyzing data from a random 50 percent sample of urban residents 65 years old and above.5

Higher AD Incidence in People Given mRNA COVID Shots

According to researchers conducting the large study:

Participants were divided into vaccinated and unvaccinated groups, with vaccinations including mRNA and cDNA vaccines. The study focused on AD and MCI incidences post-vaccination, identified via ICD-10 codes, using multivariable logistic and Cox regression analyses. Patients with vascular dementia or Parkinson’s disease served as controls.5

The researchers found an increased incidence of AD and MCI post-vaccination in those individuals who had been given COVID shots, but particularly those who had received mRNA (messenger ribonucleic acid) COVID shots. They found that the group that had gotten the mRNA shots showed a “significantly” higher incidence of AD (odds ratio of 1.225) and MCI (odds ratio of 2.377) compared to the unvaccinated group.5

Onset of AD Associated with Both SARS-CoV-2 Infections and COVID Shots

Based on their study, the researchers concluded that “preliminary evidence suggests a potential link between COVID-19 vaccination” and higher rates of AD and MCI, and that this warranted “further research” to “elucidate the relationship between vaccine-induced immune responses and neurodegenerative processes.” They stressed the need for “continuous monitoring and investigation into the vaccines’ long-term neurological impacts.”5

Clinical doctors and pathologists have observed the onset of AD in a variety of patients, including young adults, after being infected with the SARS-CoV-2 virus, but also after having been injected with COVID shots. An article in New Medical last year noted:

A viral infection with SARS-CoV-2 or even an anti-Covid-19 vaccination causes a dysfunction of the RAS (renin-angiotensin system), via an excess of the hormone angiotensin-2 normally degraded by the receptor ECA2 (angiotensin-2 converting enzyme) on which the viral or vaccine Spike protein binds and the “deleterious” overactivation of the AT1R receptor of the RAS, at the origin of Covid-19 diseases.

The overactivated AT1R receptor is pro-hypertensive, which means it provokes arterial hypertension. This impacts the brain function. Evidently, arterial hypertension has been identified as a significant risk factor for mild to severe neurodegenerative disorders such as dementia and Alzheimer’s disease.4

COVID Shot Side Effects Linked to a Number of Brain Disorders

In other studies that have shown a link between link between COVID shots and neurological side effects researchers have investigated cases of cerebral venous sinus thrombosis in women of childbearing age, Bell’s palsy, transverse myelitis, acute disseminated encephalomyelitis, and Guillain-Barré syndrome (GBS), which have developed after COVID shots.1 2 3

One study, published in the journal Brain, Behavior, & Immunity – Health in 2022, focused on “cognitive deficits and memory impairments” following receipt of AstraZeneca/Oxford University’s Covishield vaccine. In that study, the researchers concluded:

The onset of acute cognitive deficits and memory impairments could be another complication that physicians and neurologists need to be alerted to, although larger and further studies are needed to determine whether post-vaccination rates of memory impairment are common or not.2

The study recommended continued monitoring of COVID shots and “describing side effects associated with them” as being “essential to improve safety profiles and enhance public trust.”2


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Click here to view References:

1 Chatterjee A, Chakravarty A. Neurological Complications Following COVID-19 Vaccination. Curr Neurol Neurosci Rep 2023; 23(1): 1–14.
2 Chaurasia B, Chavda V, Lu B, Garg K, Montemurro N. Cognitive deficits and memory impairments after COVID-19 (Covishield) vaccination. Brain Behav Immun Health July 2022; 22: 100463.
3 Garg RK, Paliwal VK. Spectrum of neurological complications following COVID-19 vaccination. Neurol Sci 2022; 43(1): 3–40.
4 News-Medical.Net. The link between Covid-19 and Alzheimer’s disease established. June 21, 2023.
5 Roh JH, Jung I, Suh Y, Kim MH. A potential association between COVID-19 vaccination and development of Alzheimer’s disease. QJM: An International Journal of Medicine May 28, 2024.

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