My name is Professor Angus Dalgleish. I am an oncologist and immunologist with decades of experience in cancer immunotherapy and HIV research, including early clinical use of cancer immunotherapy in the United Kingdom long before checkpoint inhibitors were approved. I am Professor Emeritus and Foundation Chair of Oncology at the University of London, and Principal of the Institute of Cancer Vaccines and Immunotherapy. Beginning in late 2021, I observed a series of unexpected cancer relapses and unusually aggressive disease presentations among patients whose conditions had remained stable for years. A consistent pattern quickly became apparent: these relapses followed repeated COVID booster administration. These were patients in long-term remission who suddenly relapsed after being advised to receive additional doses of the vaccine. Despite the seriousness of these observations, there was little willingness to openly investigate these potential safety signals.
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