Sunday, October 13, 2024

GET OUR FREE E-NEWSLETTER

“You may choose to look the other way, but you can never say again that you did not know.”

— William Wilberforce

Search

Merck and Pfizer Seek Approval for COVID-19 Antiviral Drugs

Merck's antiviral drug Molnupiravir

Merck and Pfizer have submitted Emergency Use Authorization (EUA) applications to the U.S. Food and Drug Administration (FDA) to authorize distribution of what would be the first antiviral drug specifically designed to treat COVID-19 disease.1

Merck/Ridgeback Biotherapeutics are seeking EUA approval for Molnupiravir (MK-4482/EIDD-2801), an investigational oral antiviral drug originally developed to treat influenza.2 Pfizer is seeking EUA approval for their oral antiviral candidate, Paxlovid (PF-07321332; ritonavir) for the treatment of mild to moderate COVID disease.3

Molnupiravir Comes With Risks

Molnupiravir is a polymerase inhibitor. Polymerase inhibitors stop the genetic material of a virus from being replicated by tricking the enzyme (called a polymerase) responsible for replicating the virus’s RNA by inserting errors and mutations. The mutations then get replicated over and over, until there are numerous mutations making it difficult for the virus to survive.4

Katherine Seley-Radtke, PhD, a medical chemist at the University of Maryland who specializes in antiviral drug development maintains that the drug’s mutation/error catastrophe method is effective. However, she says it is “a little bit risky, because it could also hit human host enzymes, as well.”5

Some scientific research suggests that drugs like Molnupiravir can affect other enzymes in the body when taken for longer periods of time. Although Molnupiravir is to be taken at home as four capsules twice a day for five days, for a total of 40 pills,6 Dr. Seley-Radtke says “it still causes concerns.”7

Paxlovid Combines an Older Drug With an Experimental Molecule

Pfizer’s Paxlovid antiviral pill is to be administered in combination with an older antiviral drug called ritonavir and is designed to treat mild to moderate COVID in patients at increased risk of hospitalizations or death.8

Paxlovid’s mechanism is very different from the one used in Molnupiravir. Pfizer describes how Paxlovid works…

PF-07321332 is designed to block the activity of the SARS-CoV-2-3CL protease, an enzyme that the coronavirus needs to replicate. Co-administration with a low dose of ritonavir helps slow the metabolism, or breakdown, of PF-07321332 in order for it to remain active in the body for longer periods of time at higher concentrations to help combat the virus.

PF-07321332 inhibits viral replication at a stage known as proteolysis, which occurs before viral RNA replication. In preclinical studies, PF-07321332 did not demonstrate evidence of mutagenic DNA interactions.9

Vaccination Advocates Want to Prioritize COVID Vaccinations, Not Drug Treatments

Some vaccination advocates are concerned that the COVID pills will further deter unvaccinated people from getting vaccinated, arguing that although the antiviral COVID pills may be effective in treating the infection, getting unvaccinated people to take COVID vaccines should be a priority.10

Scott Ratzan, MD, a lecturer at City University of New York (CUNY) School of Public Health, noted that, in a preliminary survey of 3,000 people led by his team, one out of every eight survey respondents said they would rather be treated with a pill after getting infected than get vaccinated.11

“The new COVID pills are a big deal but vaccinations will always be the cornerstone of our response to COVID,” Dr. Ratzan said. “The oral medication represents a significant improvement in our ability to treat COVID and avert further deaths, but we must stay focused on fully vaccinating as many people as possible. Only a vaccine can control the rate at which a virus spreads and mutates.”12


If you would like to receive an e-mail notice of the most recent articles published in The Vaccine Reaction each week, click here.

Click here to view References:

5 Responses

  1. More super-expensive garbage drugs that will not save one life and will never be proven to save any lives. Who knows, these pills might contain mRNA spike proteins or some other junk that will destroy your immune system.

    Better off to take vitamin C in large doses, magnesium, Vitamin D and a few others.

  2. Indeed the vaccine is always the cornerstone, never natural health practices (which have been successful for Covid, but nobody can say so) or even pharmaceutical treatments. Modern medicine’s cash cow is the vaccine. No vaccine has ever stopped an epidemic. God didn’t leave out something that we need that later has to be injected – especially against one’s will. God didn’t somehow “miss” that mankind would stupidly turn science against humanity in the form of a man-made virus. We need and were born with functional immune systems. And for most of us Covid has been a non-event physiologically. But the economic, emotional and now vaccine injury toll (have already had 4 heatlhy people I know die immediately after the vaccine, plus numerous others with neurological events following the vaccine) has by far become the rule. Fear sells, and we’ve all been sold a bill of goods about both the virus and the vaccine, on our way to one world government and worship at the feet of the Beast of Big Pharma.

  3. We already have Ivermectin , hydroxychloroquine which are safe and effective , I wouldn’t trust Merck and Pfizer ever , these drugs that they are preparing for market are to be taken because of the adverse effects of their jab that should have never been authorized they are nothing but death and misery jabs and now they want to sell you an expensive drug to combat their failed jab , they should all be held for crimes against humanity .

    1. We should have always been looking for treatment, it is absurd that this has been so delayed. Treatments that were being tried just got so much bad press. When are doctors going to be given rights to practice medicine again?

Leave a Reply

Your email address will not be published. Required fields are marked *

Search in Archive