Moderna’s COVID-19 Vaccine Provokes ‘COVID-Like Symptoms’ in Phase 3 Trial
Biotechnology firm Moderna, Inc. of Cambridge, Massachusetts began a Phase 3 human clinical trial to test the safety and efficacy of its experimental mRNA-1273 COVID-19 vaccine on July 27, 2020. The randomized, placebo-controlled trial involves giving two 100-microgram doses of the vaccine to 28,618 volunteer participants over 18 years of age, including some elderly people […]
Johnson & Johnson Pauses Phase 3 COVID-19 Vaccine Trial Following ‘Unexplained Illness’
Story Highlights Weeks after Johnson & Johnson announced that their experimental COVID-19 vaccine was in final, Phase 3 testing, the company has paused the study to evaluate an unexplained illness in a study participant. AstraZeneca’s late-stage vaccine trial is also still on pause in the U.S. after two cases of a neurological illness arose in […]
20 Volunteers Suffer Serious Reactions to Johnson & Johnson’s COVID-19 Vaccine
On Sept. 23, 2020, U.S. pharmaceutical and medical devices company Johnson & Johnson, Inc. announced the start of the Phase 3 human clinical trial for its experimental Ad26.COV2.S vaccine for COVID-19. The New Jersey-based company, which is partnering with its subsidiary Janssen Pharmaceutica NV of Belgium on development of the vaccine, is planning to enroll […]
Baby Girl Dies in Vietnam Hours After Getting Japanese Encephalitis Vaccine
A 12-month-old baby girl died on Sept. 15, 2020 in Dong Nai, Vietnam hours after receiving a second dose of the Japanese Encephalitis (JE) vaccine at the Hiep Phuoc medical clinic. The child had received a first dose of the vaccine on July 7, 2020.1 2 3 The child became ill shortly after she was […]
WHO: Polio Outbreak in Sudan Caused by Oral Polio Vaccine
The World Health Organization (WHO) recently reported that a new poliovirus outbreak in Sudan is linked to an ongoing string of vaccine strain polio outbreaks in Africa caused by continued use of the live attenuated oral polio vaccine (OPV).1 On Aug. 9, 2020, the Federal Ministry of Health in Sudan notified the WHO of the […]
AstraZeneca Halts, Resumes COVID-19 Vaccine Trial After Serious Neurological Event
News update, Sept. 15, 2020—U.S. regulators paused AstraZeneca’s vaccine trial in the U.S. while the National Institutes of Health (NIH) launches an investigation of its own into a serious side effect in an unnamed patient in Britain. “The highest levels of NIH are very concerned,” said Dr. Avindra Nath, intramural clinical director and a leader […]