NIH and Johnson & Johnson to Begin HIV Vaccine Trials on Humans
Story Highlights NIH, in collaboration with Johnson & Johnson, will begin HIV vaccine efficacy trials on humans in August 2019 in the U.S. Another HIV vaccine candidate, using a live attenuated herpes cytomegalovirus (CMV), is also nearing clinical trials in humans. There are serious safety concerns regarding live attenuated vaccines and numerous cases reported in […]
Artificial Intelligence Takes Over Vaccine Development
Story Highlights A computer with artificial intelligence (AI) has designed a new “turbocharged” flu vaccine without human help. A research team from Flinders University in Australia created the AI program, which they named SAM (Search Algorithm for Ligands). The AI vaccine research work is being funded by the U.S. National Institutes of Health. Scientists in […]
Merck Plans to Up Production of Experimental Ebola Vaccine
In response to the current outbreak of Ebola in the Democratic Republic of the Congo (DRC) which began in August 2018, the World Health Organization (WHO) has declared the outbreak a Public Health Emergency of International Concern (PHEIC). There have been about 2,500 confirmed cases of Ebola in the DRC and at least 1,737 people have […]
Lyme Disease Vaccines: Past and Future
Story Highlights A new Lyme disease vaccine candidate approved by the FDA using the fast track process is currently in its second phase of clinical trials. In 1998, the FDA granted licensure for a Lyme disease vaccine called LYMErix. Following reports of severe adverse reactions to LYMErix, GlaxoSmithKline (formerly SmithKline Beecham) withdrew the vaccine from […]
Quest for Alzheimer’s Vaccine Hitting Roadblocks
Story Highlights Developing a vaccine for Alzheimer’s disease (AD) has been an elusive quest for pharmaceutical research companies for more than 20 years, generally focusing on preventing accumulation of amyloid plaques and tau tangles, two of the most prevalent hallmarks of the disease. A highly anticipated experimental Alzheimer’s vaccine was pulled from pre-clinical testing when […]
FDA Approves 6 in 1 Combo Vaccine for Babies
Story Highlights On Dec. 21, 2018, the U.S. Food and Drug Administration (FDA) approved a new combination hexavalent vaccine (Vaxelis) that includes antigens for six diseases to be given in three doses to infants and children between six weeks and four years of age. Manufacturers Sanofi Pasteur and Merck jointly developed Vaxelis, which combines diphtheria, […]
