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Paxlovid May Interact With Common Heart Drugs and Cause Blood Clots, Bleeding, Arrhythmia and Muscle Weakness

Paxlovid May Interact With Common Heart Drugs and Cause Blood Clots, Bleeding, Arrhythmia and Muscle Weakness

Findings from a new study published in the Journal of American College of Cardiology found that administration of the anti-viral drug Paxlovid can interact with several commonly prescribed cardiovascular drugs and be associated with an increased risk for blood clots and bleeding, which are termed clinically relevant drug-to-drug interactions (DDI).1 Manufactured by Pfizer, Paxlovid is […]

FDA Authorizes COVID Bivalent Shots for Children as Young as Five Years Old

FDA Authorizes COVID Bivalent Shots for Children as Young as Five Years Old

On Oct. 12, 2022, the U.S. Food and Drug Administration (FDA) granted an Emergency Use Authorization (EUA) of the COVID bivalent booster versions of messenger RNA (mRNA) Comirnaty and Spikevax biologics developed by Pfizer/BioNTech and Moderna/NIAID for children as young as five or six years old, respectively. The FDA’s  decision on Aug. 31 to grant […]

Safety and Effectiveness of New COVID Bivalent Boosters Based on a Study of Eight Mice?

Safety and Effectiveness of New COVID Bivalent Boosters Based on a Study of Eight Mice?

With no safety and efficacy evidence from human clinical trials, on Aug. 31, 2022, the U.S. Food and Drug Administration (FDA) amended the Emergency Use Authorizations (EUAs) for Pfizer/BioNTech’s Comirnaty and Moderna/NIAID’s Spikevax messenger RNA (mRNA) COVID-19 biologics to distribute “bivalent formulations” (two-in-one) of the shots to use as a “single booster dose.”1 2 The […]

Developers of mRNA COVID Shots Spar Over Intellectual Property Rights

Developers of mRNA COVID Shots Spar Over Intellectual Property Rights

Pfizer and BioNTech will have to answer in court to legal claims by Moderna that they copied its innovative messenger RNA (mRNA) technology in the making of their COVID-19 biologic, Comirnaty. The patent infringement lawsuit filed in U.S. District Court for the District of Massachusetts and the Regional Court of Dusseldorf in Germany alleges that […]

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