Pfizer, BioNTech End mRNA COVID-19 Biologic Trial Early
After failing to recruit enough eligible volunteers to generate enough data in the U.S. to meet U.S. Food and Drug Administration (FDA) post-marketing evidence requirements, Pfizer, Inc. and BioNTech SE have halted a large clinical trial of their updated mRNA COVID-19 biologic. The study targeted healthy adults 50 to 64 years of age but fell […]
Changes in Eye Health Linked to mRNA COVID-19 Shots
A recent prospective study published in 2025 in Ophthalmic Epidemiology has identified measurable changes in the cornea of the eye following receipt of mRNA COVID-19 biological, raising new questions about potential effects on eye health. Researchers observed differences in corneal thickness and endothelial cell characteristics in healthy adults after two doses of Pfizer/BioNTech’s Comirnaty COVID […]
Study Finds COVID Shots Harm Kidneys
A new retrospective cohort study of nearly 2.9 million adults using the TriNetX global health database—a large, privacy-compliant network of real-world clinical data from major health care organizations across multiple countries—found that individuals who received an mRNA COVID-19 shot experienced significantly higher rates of acute kidney injury and need for dialysis over a 12-month period […]
FDA May Investigate DNA Contamination in COVID Shots
The U.S. Food and Drug Administration (FDA) is considering investigating potential DNA contamination in mRNA COVID-19 shots. Tracy Beth Hoeg, MD, senior adviser to FDA commissioner Marty Makary, MD, MPH, confirmed that the investigation is “something that’s being discussed.”1 Retsef Levi, PhD, chair of the U.S. Centers for Disease and Prevention’s (CDC) COVID-19 immunization workgroup, […]
Higher Cancer Rates Found After Receipt of COVID-19 Shots
A new, peer-reviewed study by researchers in South Korea has found that people who received COVID-19 shots showed significantly higher rates of developing several cancers—including thyroid, stomach, colon, lung, breast, and prostate—compared to unvaccinated individuals. The research, published on Sept. 26, 2025 in the journal Biomarker Research, was authored by South Korean medics in orthopedic […]
Cancer Treatments Using mRNA Technology Targeted as COVID Shots Sales Decline
BioNTech SE and Moderna, Inc., two leading pharmaceutical companies that developed the mRNA COVID-19 biological, are facing new financial and regulatory challenges as demand for COVID booster shots continues to fall and U.S. health policy changes reshape the vaccine market.1 Moderna cut its 2025 sales forecast to between $1.5 billion and $2.2 billion, down as […]