Merck Plans to Up Production of Experimental Ebola Vaccine

Merck Plans to Up Production of Experimental Ebola Vaccine

In response to the current outbreak of Ebola in the Democratic Republic of the Congo (DRC) which began in August 2018, the World Health Organization (WHO) has declared the outbreak a Public Health Emergency of International Concern (PHEIC). There have been about 2,500 confirmed cases of Ebola in the DRC and at least 1,737 people have […]

Lyme Disease Vaccines: Past and Future

Lyme Disease Vaccines: Past and Future

Story Highlights A new Lyme disease vaccine candidate approved by the FDA using the fast track process is currently in its second phase of clinical trials. In 1998, the FDA granted licensure for a Lyme disease vaccine called LYMErix. Following reports of severe adverse reactions to LYMErix, GlaxoSmithKline (formerly SmithKline Beecham) withdrew the vaccine from […]

Quest for Alzheimer’s Vaccine Hitting Roadblocks

Quest for Alzheimer’s Vaccine Hitting Roadblocks

Story Highlights Developing a vaccine for Alzheimer’s disease (AD) has been an elusive quest for pharmaceutical research companies for more than 20 years, generally focusing on preventing accumulation of amyloid plaques and tau tangles, two of the most prevalent hallmarks of the disease. A highly anticipated experimental Alzheimer’s vaccine was pulled from pre-clinical testing when […]

FDA Approves 6 in 1 Combo Vaccine for Babies

FDA Approves 6 in 1 Combo Vaccine for Babies

Story Highlights On Dec. 21, 2018, the U.S. Food and Drug Administration (FDA) approved a new combination hexavalent vaccine (Vaxelis) that includes antigens for six diseases to be given in three doses to infants and children between six weeks and four years of age. Manufacturers Sanofi Pasteur and Merck jointly developed Vaxelis, which combines diphtheria, […]

Vaccine for Bees Bypasses Lack of Antibodies

Vaccine for Bees Bypasses Lack of Antibodies

Story Highlights Bees and other pollinators face serious threats from disease, parasites, pesticides and habitat destruction, threatening the viability of crop farming worldwide, most well publicized by the critical danger posed to honeybees. Treatment of bee diseases has been hampered by the nature of the honeybee immune system: They do not produce targeted antibodies as […]

AFM Not Transmissible from Human to Human Says CDC

AFM Not Transmissible from Human to Human Says CDC

The Centers for Disease Control and Prevention (CDC) still does not know what is causing the growing number of cases of acute flaccid myelitis (AFM) in the United States, but it believes the polio-like illness is not contagious. In a recent interview with CBS, CDC director Robert Redfield, MD said, “The good news is that it […]

Vaccine for Acne Targets Bacteria in the Skin’s Microbiome

Vaccine for Acne Targets Bacteria in the Skin’s Microbiome

Story Highlights Current acne treatments such as antibiotics, birth control pills, etc., have largely proven to be ineffective. A proposed vaccine to treat acne targets toxins secreted by a specific bacteria, P.acnes, which lives on the skin and is a part of the skin’s natural mircobiome. Concerns have been raised regarding the vaccine because of […]

Vaccinating Plants: A Risky Technology?

Vaccinating Plants: A Risky Technology?

In an attempt to reduce use of pesticides on crops, scientists are exploring the concept of “vaccinating” food plants to prevent them from being infected with viruses and other pathogens. Experiments are utilizing an external application of double-stranded RNA (dsRNA), a naturally occurring product that is found in most organisms, to make plants resistant to certain microbes.

WHO Recommends New Typhoid Vaccine

WHO Recommends New Typhoid Vaccine

The World Health Organization (WHO) has announced that infants and children can be given a new typhoid conjugate vaccine when it is released in 2019. After collecting five years of follow-up observation data for seroconversion, WHO officials put forward recommendations to introduce the first typhoid conjugate vaccine for infants and children over six months of age as a single dose.

White House Backs Development of Heroin Vaccine

White House Backs Development of Heroin Vaccine

On Mar. 19, 2018, the White House announced the “President Donald J. Trump’s Initiative to Stop Opioid Abuse and Reduce Drug Supply and Demand.” The program will include “supporting research and development for a vaccine to prevent opioid addiction and non-addictive pain management options.”