Quest for Universal Flu Vaccine Boosted by $200M NIH Grant to University of Maryland

Quest for Universal Flu Vaccine Boosted by $200M NIH Grant to University of Maryland

Story Highlights National Institutes of Health (NIH) has awarded the University of Maryland a contract for more than $200 million to develop a universal influenza vaccine. Currently, the influenza vaccine used around the world is developed every year by drug companies based on the “best guesses” made by public health officials at the World Health […]

Kenya Launches Malaria Vaccine Pilot Program

Kenya Launches Malaria Vaccine Pilot Program

Kenya has become the third African country, along with Ghana and Malawi, to launch a pilot program for the world’s first malaria vaccine, Mosquirix, which has been developed by GlaxoSmithKline (GSK). The vaccine is available to children from six months of age in specific locations in Kenya due to its phased pilot introduction.1 2 Malaria […]

Executive Order Creates Influenza Vaccine Task Force to Promote “National Security and Public Health”

Executive Order Creates Influenza Vaccine Task Force to Promote “National Security and Public Health”

On Sept. 19, 2019, President Donald Trump signed an Executive Order, “Modernizing Influenza Vaccines in the United State to Promote National Security and Public Health.” Describing mass use of influenza vaccines “to combat seasonal flu” and influenza pandemics as “strengthening our Nation’s public health and security,” he announced the establishment of a National Influenza Vaccine […]

Vaccine for Inflammation in the Works

Vaccine for Inflammation in the Works

Story Highlights Scientists are working on a vaccine for autoimmune, inflammation-induced mental health issues using soil-derived bacteria. Vaccines have been implicated in increasing the risk for neuropsychiatric issues in children. Vaccines and all other immune-system activators act by provoking an inflammatory response. Christopher Lowry, PhD and a team of researchers from the University of Colorado […]

NIH and Johnson & Johnson to Begin HIV Vaccine Trials on Humans

NIH and Johnson & Johnson to Begin HIV Vaccine Trials on Humans

Story Highlights NIH, in collaboration with Johnson & Johnson, will begin HIV vaccine efficacy trials on humans in August 2019 in the U.S. Another HIV vaccine candidate, using a live attenuated herpes cytomegalovirus (CMV), is also nearing clinical trials in humans. There are serious safety concerns regarding live attenuated vaccines and numerous cases reported in […]

Artificial Intelligence Takes Over Vaccine Development

Artificial Intelligence Takes Over Vaccine Development

Story Highlights A computer with artificial intelligence (AI) has designed a new “turbocharged” flu vaccine without human help. A research team from Flinders University in Australia created the AI program, which they named SAM (Search Algorithm for Ligands). The AI vaccine research work is being funded by the U.S. National Institutes of Health. Scientists in […]

Merck Plans to Up Production of Experimental Ebola Vaccine

Merck Plans to Up Production of Experimental Ebola Vaccine

In response to the current outbreak of Ebola in the Democratic Republic of the Congo (DRC) which began in August 2018, the World Health Organization (WHO) has declared the outbreak a Public Health Emergency of International Concern (PHEIC). There have been about 2,500 confirmed cases of Ebola in the DRC and at least 1,737 people have […]

Lyme Disease Vaccines: Past and Future

Lyme Disease Vaccines: Past and Future

Story Highlights A new Lyme disease vaccine candidate approved by the FDA using the fast track process is currently in its second phase of clinical trials. In 1998, the FDA granted licensure for a Lyme disease vaccine called LYMErix. Following reports of severe adverse reactions to LYMErix, GlaxoSmithKline (formerly SmithKline Beecham) withdrew the vaccine from […]

Quest for Alzheimer’s Vaccine Hitting Roadblocks

Quest for Alzheimer’s Vaccine Hitting Roadblocks

Story Highlights Developing a vaccine for Alzheimer’s disease (AD) has been an elusive quest for pharmaceutical research companies for more than 20 years, generally focusing on preventing accumulation of amyloid plaques and tau tangles, two of the most prevalent hallmarks of the disease. A highly anticipated experimental Alzheimer’s vaccine was pulled from pre-clinical testing when […]

FDA Approves 6 in 1 Combo Vaccine for Babies

FDA Approves 6 in 1 Combo Vaccine for Babies

Story Highlights On Dec. 21, 2018, the U.S. Food and Drug Administration (FDA) approved a new combination hexavalent vaccine (Vaxelis) that includes antigens for six diseases to be given in three doses to infants and children between six weeks and four years of age. Manufacturers Sanofi Pasteur and Merck jointly developed Vaxelis, which combines diphtheria, […]