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BARDA Awards $9.27 Million Contract to Evaluate Oral Pill COVID Vaccine

woman taking a pill

Biotechnology firm Vaxart, Inc. announced on Jan. 19, 2024 that it received a $9.27 million contract from the U.S. Biomedical Advanced Research and Development Authority (BARDA) to fund preparations for a Phase IIb clinical trial to evaluate the company’s oral pill XXB COVID-19 vaccine candidate. The trial is expected to involve 10,000 participants and will […]

Only Remaining HIV Vaccine Efficacy Trial Fails in Africa

The latest effort to develop an HIV (human immunodeficiency viruses) vaccine in Uganda, Tanzania and South Africa was halted on Dec. 6, 2023 after preliminary data showed that the vaccine would not be effective at preventing HIV infection. The PrEPVacc (pre-exposure prophylaxis vaccine) phase 2b trial was testing two different combinations of experimental HIV vaccines, […]

Oral Vaccine for COVID Under Development in Japan

COVID vaccine pill

Researchers in Japan have been working on a new vaccine for COVID-19 that would be administered orally rather than by injection. The vaccine, under development by EPS Holdings, Inc. of Tokyo, is in the form of a pill that is placed under the tongue and contains part of the spike protein along with an adjuvant […]

U.S. Taxpayers Fund $5 Billion Project NextGen to Develop Novel COVID Vaccines and Drugs

more money for more COVID vaccines

Just three months after the Biden administration announced that U.S. taxpayers would fund a $5 billion initiative called Project NextGen to develop “next generation” COVID-19 vaccines and therapeutics, the U.S. Department of Health and Human Services’ (HHS) awarded $1.4 billion in contracts under the program on Aug. 22, 2023. The total includes “$1 billion for […]

Novel mRNA Lyme Shots Could Be Released in 2025

test tube and tick

Two novel messenger RNA (mRNA) shots for Lyme disease currently in late-stage clinical trials could hit the market as early as 2025, Moderna announced earlier this year. Also in the race to develop the first-ever mRNA product to prevent Lyme disease are Pfizer and Austria-based Valneva, which entered into a collaborative agreement in April 2020 […]

3D Printed Vaccine Skin Patches Being Developed

microneedle skin patch

In an attempt to increase consumer demand for COVID-19 shots, researchers have designed a vaccine printer that can print COVID messenger RNA (mRNA) skin patches in bulk, producing as many as 100 patches in 48 hours. The microneedle patches, which contain mRNA molecules in lipid nanoparticles, could pave the way for unlimited distribution of the […]

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